Valve & Structural Heart Disease Center

Valve & Structural Heart Disease Center - View Full PDF


University Hospitals Harrington Heart & Vascular Institute


Marco Costa, MD, PhD, Interventional Cardiology
Alan Markowitz, MD, Cardiac Surgery


Guilherme Attizzani, MD
Angela Davis, RN


Please call Program Coordinator Katherine Burns at 216-844-8448 for appointments and transfers.

Conditions Treated

  • Aortic stenosis
  • Mitral regurgitation
  • Mitral stenosis
  • Atrial septal defect (ASD)
  • Patent foramen ovale (PFO) paradoxical stroke


  • Transcatheter aortic valve replacement (TAVR)
  • Surgical aortic valve replacement (SAVR)
  • Valve-in-valve for bioprosthetic valve failure (aortic valve, mitral valve)
  • MitraClip
  • Surgical mitral valve replacemen
  • Mitral/aortic balloon valvuloplasty
  • ASD closure (catheter and surgical)
  • PFO closure (catheter)
  • Left ventricular restoration therapy (LV Parachute)

Distinguishing Features

  • Multidisciplinary heart team with cardiac surgery and interventional cardiology working side by side
  • TAVR in “awake and talking” patient: catheterization lab-based procedure with conscious sedation and > 95 percent percutaneous femoral access; average length of stay only two to three days; high-volume center performing more than 200 procedures annually
  • Leading-edge technologies with partner hospitals in Europe for earliest technology access
  • Edwards Center of Excellence and Medtronic Center of Excellence for physician TAVR training
  • National training center for interventional fellows


About UH Cleveland Medical Center
At the core of University Hospitals’ $4 billion health system is UH Cleveland Medical Center, ranked among America’s best hospitals by U.S. News & World Report. UH Cleveland Medical Center is home to some of the most prestigious clinical and research programs in the nation, including cancer, pediatrics, women’s health, orthopedics, radiology, neuroscience, cardiology and cardiovascular surgery, digestive health, transplantation and genetics. Its main campus includes UH Rainbow Babies & Children’s Hospital, ranked among the top children’s hospitals in the nation; UH MacDonald Women’s Hospital, Ohio’s only hospital for women; and UH Seidman Cancer Center, part of the NCI-designated Case Comprehensive Cancer Center at Case Western Reserve University.