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Heart & Vascular Research and Clinical Trials

The Research & Innovation Center of the UH Harrington Heart & Vascular Institute was established in 2006 in affiliation with the Case Cardiovascular Research Institute to foster discoveries in cardiovascular disease, therapies and technologies. Our physician-scientists are at the forefront of translating cardiovascular discoveries into improved patient care.

  • 70 faculty, fellows and staff conducting cardiovascular research with committed federally funded research exceeding $32 million
  • 92 human clinical trials (2,700 total enrolled patients) investigating novel therapies for heart failure, arrhythmia, coronary and peripheral arterial disease
  • A nationally recognized adult, nonembryonic, stem cell research center and leader of the Ohio Cell-based Therapy Consortium
  • One of the most comprehensive cardiovascular imaging programs in the nation with state-of-the-art nuclear medicine, MRI, CT, vascular, cardiac catheterization and electrophysiology laboratories, including the novel Stereotaxis, NOGA and robotic 3-D navigation systems
  • World’s premier program in optical coherence tomography (OCT), a novel vascular imaging technology that provides micron-scale images of the coronary arteries
  • One of the largest calcium score preventive and therapeutic programs in the nation
  • One of 45 sites nationally exploring expanded indications for transcatheter aortic valve replacement (TAVR, i.e., low and intermediate risk)

For more information on active clinical trials, contact Stacey Mazzurco, RN, Clinical Research Director, at 216-844-3130 or

Featured Research

Educating patients about cancer treatment clinical trials improves knowledge and attitudes about participating in research

February 28, 2016

Case Western Reserve School of Medicine and University Hospitals researchers find video-based information more effective than text in encouraging participants to consider clinical trials